Women's sexual satisfaction isn't usually in the forefront of the intimacy dialogue. Men's ED medications are popular, highly marketed, and everywhere you look. However, many women notice shifts in sexual desire, arousal, and satisfaction at different stages of life.
Stress, hormonal changes, medications, and medical conditions can all play a role. Because intimate health is strongly intertwined with overall wellbeing, a growing number of clinicians are exploring both lifestyle changes and evidence-based medications to help women feel more connected, confident, and fulfilled.
Three compounds sometimes discussed in this context are Tadalafil (the generic form of Cialis), PT-141 (bremelanotide), and oxytocin.
Tadalafil (Generic Cialis): Improving Blood Flow and Response
Tadalafil is a PDE-5 inhibitor approved for erectile dysfunction in men. In women, it’s thought to work by improving blood flow to the pelvic region, which may enhance sensitivity and sexual response.
A few small studies and case reports, particularly in women experiencing sexual side effects from antidepressants or menopause. suggest potential benefits for arousal and lubrication.
PT-141 (Bremelanotide): Targeting Desire Through the Brain
PT-141, also known as bremelanotide, is a melanocortin receptor agonist that acts on the central nervous system. It is FDA-approved as an on-demand injectable treatment for hypoactive sexual desire disorder (HSDD) in premenopausal women.
Some compounding pharmacies offer PT-141 in sublingual forms, but these are not FDA-approved and have limited clinical data. In pivotal trials with the injectable form, women reported an increase in satisfying sexual events per month compared to placebo. Side effects can include nausea, flushing, and increases in blood pressure, so medical monitoring is essential.
Oxytocin: Enhancing Connection and Relaxation
Oxytocin is a naturally occurring neuropeptide often called the “bonding hormone” because of its role in labor, breastfeeding, and social attachment. Researchers have studied intranasal and sublingual oxytocin for potential effects on sexual satisfaction, orgasm intensity, and emotional closeness.
Sublingual Delivery: Fast & Discreet
Placing medications under the tongue can lead to faster absorption and bypass some digestive breakdown. Compounded sublingual forms of these agents are popular for their convenience and efficacy.
Taking a Holistic View of Intimate Health
Medications like tadalafil, PT-141, and oxytocin may offer new avenues for women struggling with sexual challenges. But they work best when combined with a broader focus on wellbeing: addressing stress, relationship factors, hormones, and lifestyle.
Our Arousal Melts for Her combine these three medications in a safe and effective dose, helping women increase higher levels of sexual gratification.
